Laser based Microdissection:
The MMI CellCut is the user-friendly laser microdissection tool to isolate groups of cells, single cells, and cell components for analysis across a wide range of applications.The CellCut is contamination free, reproducible and reliable and optimised for high quality and quantity DNA, RNA, Protein recovery.

Standard solid state UV cutting Laser :
• Wavelength 355 nm
• Maintenance free
• Extremely sharp focus due to computer simulated optics
• Safety devices and eye protection filters
• Laser Technology: Actively Q-switched
• Pulse duration <500ps
• Pulse energy >1µJ
• Pulse frequency up to 2kHz

MMI Isolation Cap & MMI Single CapLift
• Patented, contamination free method for isolation of microdissected areas using adhesive cap technology with pre-defined target positioning (PTP) and positive sample inspection
• Software controlled positioning, lifting and lowering of adhesive cap
• Removable Plug & play module for full access to the microscope stage
• Adjustable contact pressure between cap and slide
• 3 cap holders with magnetic mount for 0.2ml, 0.5ml and 1.5ml

MMI CellCut software functions
• Computer controlled laser power, focus position and cutting speed
• Free-hand drawing or predefined figures: circles, squares, ellipses
• Multi-segment drawing for objects larger than the field of view
• Automatic cutting of marked areas and collecting of dissected samples, including multi cutting option
• Group cutting functions incl. group statistics
• Automatic documentation with immediate access to report
• Serial section function: allows the marking of target regions onto one or more unstained sections by using a stained top section as a template. Differences in shape, angle and position are automatically compensated by the software giving highly accurate results.
• Z-Drill function: Cutting of wet and thick tissue without the need for increased laser power. The laser is refocused through the sample and so facilitates cutting in a spiral.

MMI Consumables Starter Kit CellCut
• Various MMI Caps, MMI Slides and MMI Consumables for first use

Laser based Microdissection:
The MMI CellCut is the user-friendly laser microdissection tool to isolate groups of cells, single cells, and cell components for analysis across a wide range of applications.The CellCut is contamination free, reproducible and reliable and optimised for high quality and quantity DNA, RNA, Protein recovery.

Universal solid state UV cutting Laser :
4 times more power compared to the standard laser. Can also cut thicker CTC filters and thicker biological material.
• Wavelength 355 nm
• Maintenance free
• Extremely sharp focus due to computer simulated optics
• Safety devices and eye protection filters
• Laser technology: Actively Q-switched
• Pulse duration <500ps
• Pulse energy >2µJ
• Pulse frequency up to 4kHz

MMI Isolation Cap & MMI Single CapLift
• Patented, contamination free method for isolation of microdissected areas using adhesive cap technology with pre-defined target positioning (PTP) and positive sample inspection
• Software controlled positioning, lifting and lowering of adhesive cap
• Removable Plug & play module for full access to the microscope stage
• Adjustable contact pressure between cap and slide
• 3 cap holders with magnetic mount for 0.2ml, 0.5ml and 1.5ml

MMI CellCut software functions
• Computer controlled laser power, focus position and cutting speed
• Free-hand drawing or predefined figures: circles, squares, ellipses
• Multi-segment drawing for objects larger than the field of view
• Automatic cutting of marked areas and collecting of dissected samples, including multi cutting option
• Group cutting functions incl. group statistics
• Automatic documentation with immediate access to report
• Serial section function: allows the marking of target regions onto one or more unstained sections by using a stained top section as a template. Differences in shape, angle and position are automatically compensated by the software giving highly accurate results.
• Z-Drill function: Cutting of wet and thick tissue without the need for increased laser power. The laser is refocused through the sample and so facilitates cutting in a spiral.

MMI Consumables Starter Kit CellCut
• Various MMI Caps, MMI Slides and MMI Consumables for first use

Laser based Microdissection:
The MMI CellCut is the user-friendly laser microdissection tool to isolate groups of cells, single cells, and cell components for analysis across a wide range of applications.The CellCut is contamination free, reproducible and reliable and optimised for high quality and quantity DNA, RNA, Protein recovery.

For cutting extremly hard materials like plants, bone, bone marrow, teeth, forensic tapes etc.
Solid state UV laser:
• Wavelength 343 nm
• Maintenance free
• Guaranteed life span 1 year or 2 Gigashot whatever comes first
• Extremely sharp focus via computer simulated optics
• Safety devices and eye protection filters
• Laser technology: Actively Q-switched
• Pulse duration < 1,3ns
• Pulse energy > 100μJ
• Pulse frequency up to 500Hz
• Max power = 50mW


MMI Isolation Cap & MMI Single CapLift
• Patented, contamination free method for isolation of microdissected areas using adhesive cap technology with pre-defined target positioning (PTP) and positive sample inspection
• Software controlled positioning, lifting and lowering of adhesive cap
• Removable Plug & play module for full access to the microscope stage
• Adjustable contact pressure between cap and slide
• 3 cap holders with magnetic mount for 0.2ml, 0.5ml and 1.5ml

MMI CellCut software functions
• Computer controlled laser power, focus position and cutting speed
• Free-hand drawing or predefined figures: circles, squares, ellipses
• Multi-segment drawing for objects larger than the field of view
• Automatic cutting of marked areas and collecting of dissected samples, including multi cutting option
• Group cutting functions incl. group statistics
• Automatic documentation with immediate access to report
• Serial section function: allows the marking of target regions onto one or more unstained sections by using a stained top section as a template. Differences in shape, angle and position are automatically compensated by the software giving highly accurate results.
• Z-Drill function: Cutting of wet and thick tissue without the need for increased laser power. The laser is refocused through the sample and so facilitates cutting in a spiral.

MMI Consumables Starter Kit CellCut
• Various MMI Caps, MMI Slides and MMI Consumables for first use

Capillary based Cell-Sorting:
The MMI CellEctor is an integrated instrumentation solution for the fully manual or automated recognition, aspiration and deposition of single cells in suspension onto a wide range of cell culture or molecular biology device.

MMI CellEctor 3D Robot
• 3 Axis fully motorized and software controlled
• Easy swivel device to allow full access to the stage
• Easily adjustable capillary position (both along and around its axis)
• Patented capillary protection

High Precision MMI CellPump
Motorized and software controlled high precision pump to acquire and deposit cells or particles in defined volumes consisting of:
• MMI CellPump with 2 nanoliter resolution
• Pump filling and maintenance accessories
• Integrated protection from mechanical damage
• Seamless switching between manual and motorized mode
• Patented design for easy fill and flush

MMI CellEctor software functions
• Fully automated or manual acquisition and deposition of cells
• Choice of three automation levels including full automation with scanning of the sample and cell recognition
• Complex movement modes of the capillary (skipping of the sample container wall, user-defined immersion and deceleration distance, deposition at vertical walls)
• User-defined spacing between the capillary tip and the slide with a dynamic correction to compensate the slide tilt
• Automated capillary re-focusing options: on the microscope slide or on the capillary tip
• user-defined pump parameter sets for different capillary diameters
• Automated dispatching of cells onto either grids or any other device (e.g. a PCR tube, cell culture vessel)
• Automated inspection of loaded grids (spot by spot) with cells recognition and statistics report
• Automated reduction of excitation times under fluorescence settings

MMI Consumables Starter Kit CellEctor
• Various MMI capillaries and additional MMI consumables for first use

Trainable Image Analysis Software:
• Automatic recognition of objects based on the structure and color of training objects
• Postprocessing to limit sizes, and borders and smothen shapes
• Splitting adjecent cells
• Can be applied for all cell types defined
• Logical combination between cell types
• Fully integrated imaging plug-in – i.e. identified objects can processed with mmi CellCut or mmiCellEctor
• Manual selection of the identified objects

25mm x 75mm slide scan in less than 10min with 20x objective, including full resolution digital slide image saved on disk.

Full resolution whole slide image
• Stitching of a huge full resolution overview image (BigTiff)
• TIFF file with full resolution layer and lower resolution layers for fast preview
• Full preservation of the position information
• The stitched image will be stored on the drive and can be used for external image analysis

Fast motorised stage control with improved speed and acceleration
• speed > 50mm/sec (for MMI stages with 2mm pitch screw)
• acceleration 10x higher than with standard MMI Platform

Fast CMOS camera control for MMI CellCamera VCXU23c:
• USB3 image transfer rate > 160fps (without visualisation)
• 10 min for full slide scan under 20x (guaranteed with VCXU23c and 2mm pitch screw MMI stage)
• Scan will work with every MMI Camera, but can take longer

Single click scan
• Scan all configured slides with one single button click

Automated Focus Map
• Multi position focusing map for precise motorised focusing during scanning process, also for uneven samples can be created fully automatically

Full slide image Viewer:
• Ultra fast slide viewing with full resolution images
• Draw your cutting areas directly into the full slide image
• Annotate fluorescence scans without bleaching

Laser Optical Tweezers:
The MMI CellManipulator uses a Ytterbium infrared laser with a long wavelength with up to 10 W of trapping power. The wavelength of the laser does not interfere with the integrity of living specimens. The intensely-focused laser beam can hold, move, rotate, join, separate, stretch or otherwise manipulate in three dimensions upto ten microscopic objects simultaneously. The particles suspended in liquid can range from 0.2 to 200 microns.

MMI CellManipulator laser specification
• New back port design with two level options, allowing multibeam trapping on two Z-levels and 10 time-shared traps per level. (Second level offered as option.)
• 10 watt high power laser 1070 nm wavelength
• Fiber coupled, allowing separate location action of light source and laser controller
• Power stability 0.1% measured at 2 kHz bandwidth
• Ultra low power optical trapping with high laser stability due to special design
• Galvo scanner set, 2 kHz controlled by MMI CellTools software
• Focus motorized and software controlled
• Ultra compact design and excellent mechanical stability

MMI CellManipulator software functions
• Laser focus and power control by slider
• Creating of the tweezers point by mouse click into the video
• Removing of the tweezers point by double mouse click
• Moving of tweezers point by dragging
• Possibility to define groups of tweezers points
• Groups can be dragged, rotated and stretched individually
• Online data acquisition, live display and data streaming to hard drive
• Trap oscillation methods for force measurement applications
• Non-essential panels can be folded away
• New force measurement and data acquisition module
• Support for PI piezo stages

MMI Consumables Starter Kit CellManipulator
• Includes Microbeads, 2x eye protection goggles, various disposables for first application use